This is yet another effective and simple method that you can try out at home. All you need is baking soda, water, and a glass. Well, mix at least 2 spoonful of baking soda in a glass containing water and let the baking soda dissolve completely. Dip the end of the bristles of your toothbrush in the resultant solution and leave it for 5 minutes. The baking soda will effectively kill the germs trapped by the bristles which make it an alternative option for those people who can’t afford Antibacterial Mouthwash.